FREE shipping to on qualifying orders when you spend or more, processed by Ossila BV. All prices ex. VAT. Qualifying orders ship free worldwide! Fast, secure, and backed by the Ossila guarantee. It looks like you are visiting from , click to shop in or change country. Orders to the EU are processed by our EU subsidiary.

It looks like you are using an unsupported browser. You can still place orders by emailing us on info@ossila.com, but you may experience issues browsing our website. Please consider upgrading to a modern browser for better security and an improved browsing experience.

2-Bromo-6-fluorobenzaldehyde

CAS Number 360575-28-6

Chemistry Building Blocks, Fluorinated Building Blocks, Monomers


Product Code B2381-5g
Price $125 ex. VAT

Quality assured

Expert support

Volume discounts

Worldwide shipping

Fast and secure


A fluorinated benzaldehyde derivative

A multi-functional building block for synthesizing ligands, bicyclic heterocycles and semiconductors


2-Bromo-6-fluorobenzaldehyde (CAS number 360575-28-6) is a benzaldehyde substituted with a bromine and a fluorine at the ortho-positions. A 1H and 19F NMR probe, fluoro-2-formyphenyl boronic acid is synthesized from 2-bromo-6-fluorobenzaldehyde. The NMR probe can determine the enantiopurity of sulfinamides that are widely used as chiral auxiliaries for asymmetric synthesis. 2-Bromo-6-fluorobenzaldehyde is used to synthesize bicyclic heterocycles such as indazoles, through a reaction of 2-bromo-6-fluorobenzaldehyde, primary amines and sodium azide, catalysed by copper(II) oxide.

2-Bromo-6-fluorobenzaldehyde can assist self-assembly of macromolecules to fabricate nanostructures. A semiconducting thienisoindigo based nanowire is assembled with 2-bromobenzaldehyde via halogen and chalcogen bonding, showing hole mobility of 6.39×10−4 cm2/Vs.

Multiple functional groups

Multiple functional groups

For facile synthesis

Fluorinated building block

Fluorinated benzaldehyde building block

For drug discovery, NMR probes and semiconducting materials

Worldwide shipping for 360575-28-6

Worldwide shipping

Quick and reliable shipping

High purity 360575-28-6

High purity

>97% High purity

General Information

CAS Number 360575-28-6
Chemical Formula C7H4BrFO
Full Name 2-Bromo-6-fluorobenzaldehyde
Molecular Weight 203.01 g/mol
Synonyms 6-Bromo-2-fluorobenzaldehyde, 2-Fluoro-6-bromobenzaldehyde
Classification / Family Fluorinated building blocks, Benzaldehyde building block, Ligands, NMR probes, Semiconductors

Chemical Structure

2-Bromo-6-fluorobenzaldehyde chemical structure, CAS 360575-28-6
2-Bromo-6-fluorobenzaldehyde chemical structure, CAS 360575-28-6

Product Details

Purity 97%
Melting Point Tm = 43  47 °C
Appearance Beige powder

MSDS Documentation

2-Bromo-6-fluorobenzaldehyde2-Bromo-6-fluorobenzaldehyde MSDS Sheet

Literature and Reviews

  1. Thienoisoindio-based semiconductor nanowires assembled with 2-bromobenzaldehyde via both halogen and chalcogen bonding, Sci. Rep., 8, 1488(2018); DOI: 10.1038/s41598-018-32486-z.
  2. A combined kinetico-mechanistic and computational study on the competitive formation of seven versus five-membered platinacycles; the relevance of spectator halide ligands, G. Aullón et al., Dalton Trans., 44, 17968–17979(2015); DOI: 10.1039/C5DT02657A.
  3. A three-component derivatization protocol for determining the enantiopurity of sulfinamindes by1H and 19F NMR spectroscopy, R. Groleau et al., J. Org. Chem., 85, 1208–1215(2020); DOI: 10.1021/acs.joc.9b02473.
  4. CuO nanoparticle catalysed synthesis of 2H-indazoles under ligand free conditions, RSC Adv., 4, 4080(2014); DOI: 10.1039/c3ra45298k.
  5. Synthesis of pyrimidine fused quinolines by ligand-free copper-catalyzed domino reactions, A. Panday et al., J. Org. Chem., 83(7), 3624–3632(2018); DOI: 10.1021/acs.joc.7b03272.

To the best of our knowledge the information provided here is accurate. The values provided are typical at the time of manufacture and may vary over time and from batch to batch. Products may have minor cosmetic differences (e.g. to the branding) compared to the photos on our website. All products are for laboratory and research and development use only.

Return to the top