FREE shipping to on qualifying orders when you spend or more, processed by Ossila BV. All prices ex. VAT. Qualifying orders ship free worldwide! Fast, secure, and backed by the Ossila guarantee. It looks like you are visiting from , click to shop in or change country. Orders to the EU are processed by our EU subsidiary.

It looks like you are using an unsupported browser. You can still place orders by emailing us on info@ossila.com, but you may experience issues browsing our website. Please consider upgrading to a modern browser for better security and an improved browsing experience.

4-Fluororesorcinol

CAS Number 103068-41-3

Fluorinated Building Blocks, Monomers


Product Code B2491-1g
Price $88 ex. VAT

Quality assured

Expert support

Volume discounts

Worldwide shipping

Fast and secure


A fluorinated resorcinol building block

Used as a synthesis intermediate for dyes, liquid crystals and APIs


4-Fluororesorcinol (CAS number 103068-41-3) is a fluorinated resorcinol, a meta-substituted benzenediol. One of the key applications of 4-fluororesorcinol is to synthesise fluorinated fluoresceins. One synthetic route is 4-fluororesorcinol reacting with benzaldehyde derivatives and followed by an oxidation by 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ). Another method includes a reaction of 4-fluororesorcinol with phthalic anhydride catalysed by zinc chloride or methanesulfonic acid. It is feasible to synthesise bent-core azo-benzene liquid crystal mesogens from 4-fluororesorcinol with a bending angle of 121.5°.

Chemical structure of fluorinated fluorescein
Chemical structure of fluorinated fluorescein, a fluorescent dye

4-Fluororesorcinol can also chelate to the copper centre in oxy-tyrosinase causing inactivation of the tyrosinase.

Multiple functional groups

Multiple functional groups

For facile synthesis

Fluorinated building block

Fluorinated resorcinol building block

For the synthesis of dyes, liquid crystals and APIs

Worldwide shipping for 103068-41-3

Worldwide shipping

Quick and reliable shipping

High purity 103068-41-3

High purity

>98% High purity

General Information

CAS Number 103068-41-3
Chemical Formula C6H5FO2
Full Name 4-Fluoro-1,3-dihydroxybenzene
Molecular Weight 128.10 g/mol
Synonyms 4-Fluoro-1,3-benzenediol
Classification / Family Fluorinated building block, Dyes, APIs, Liquid crystals

Chemical Structure

4-Fluororesorcinol chemical structure, CAS 103068-41-3.
4-Fluororesorcinol chemical structure, CAS 103068-41-3

Product Details

Purity 98%
Melting Point Tm = 96 °C – 100 °C
Appearance Beige powder

MSDS Documentation

4-Fluororesorcinol MSDS Sheet4-Fluororesorcinol MSDS Sheet

Literature and Reviews

  1. Efficient two-step synthesis of 9-aryl-6-hydroxy-3H-xanthen-3-one-fluorophores, J. Bacci et al., J. Org. Chem., 70(22), 9051–9053(2005); DOI: 10.1021/jo051243i.
  2. Dark conglomerate phases of azobenzene derived bent-core mesogens — relationships between the molecular structure and mirror symmetry breaking in soft matter, M. Alaasar et al., Soft Matter, 10, 7285(2014); DOI: 10.1039/c4sm01255k.
  3. Mechanistic studies of the inactivation of tyrosinase by resorcinol, M. Stratford et al., ioorg. Med. Chem., 21, 1166–1173(2013); DOI: 10.1016/j.bmc.2012.12.031.
  4. Synthesis of fluorinated fluoresceins, W.-C. Sun et al., J. Org. Chem., 62, 6469–6475(1997); DOI: 10.1021/jo9706178.

To the best of our knowledge the information provided here is accurate. The values provided are typical at the time of manufacture and may vary over time and from batch to batch. Products may have minor cosmetic differences (e.g. to the branding) compared to the photos on our website. All products are for laboratory and research and development use only.

Return to the top