FREE shipping to on qualifying orders when you spend or more, processed by Ossila BV. All prices ex. VAT. Qualifying orders ship free worldwide! Fast, secure, and backed by the Ossila guarantee. It looks like you are visiting from , click to shop in or change country. Orders to the EU are processed by our EU subsidiary.

It looks like you are using an unsupported browser. You can still place orders by emailing us on info@ossila.com, but you may experience issues browsing our website. Please consider upgrading to a modern browser for better security and an improved browsing experience.


Product Code B1871-LT-1g
Price £95 ex. VAT

A fluorinated heterocyclic building block

Materials synthesis in application of OLEDs, DSSCs and bioimaging


Specifications | MSDS | Literature and Reviews


8-Fluoro-4-hydroxy-2-methylquinoline (CAS number 5288-22-2) is consisting of a benzene-fused pyridine (quinoline) with 2-methyl, 4-hydroxyl and 8-fluoro substituents around the quinoline rings. 8-Fluoro-4-hydroxy-2-methylquinoline has multi-functional groups to allow facile reactions such as nucleophilic substitution and enamine condensation with an aldehyde. Quinoline is typically used to synthesize dyes for dye-sensitized solar cells (DSSCs) and OLEDs, due to its conjugated molecular structure. The energy gap of the molecule can be tuned effortlessly by functional group conversions.

The derivatives of quinoline are often bioactive, for instance, quinine is a well-known drug for malaria treatments. The active pharmaceutical ingredients can also be tailored into fluorescent bioimaging substances to monitor cell activities in vitro experiments.

Multiple functional groups

Multiple functional groups

For facile synthesis

Worldwide shipping for 5288-22-2

Worldwide shipping

Quick and reliable shipping

Fluorinated building block

Fluorinated quinoline building block

For drug discoveries, OLEDs, and solar cells

High purity 5288-22-2

High purity

>98% High purity

General Information


CAS Number 5288-22-2
Chemical Formula C10H8FNO
Full Name 8-Fluoro-2-methyl-4-quinolinol
Molecular Weight 177.18 g/mol
Synonyms 8-Fluoro-2-methylquinolin-4-ol
Classification / Family Quinoline derivatives, Heterocyclic building block, Fluorinated building block, Dyes, OLEDs, DSSCs

Chemical Structure


8-Fluoro-4-hydroxy-2-methylquinoline chemical structure, CAS 5288-22-2
8-Fluoro-4-hydroxy-2-methylquinoline, CAS 5288-22-2

Product Details


Purity >98%
Boiling Point Tm = 230 °C – 236 °C
Appearance Pale cream to pale brown powder/crystal

MSDS Documentation


8-Fluoro-4-hydroxy-2-methylquinoline8-Fluoro-4-hydroxy-2-methylquinoline MSDS Sheet

Literature and Reviews


  1. Application of quinoline derivatives in third-generation photovoltaics, G. Lewinska et al., J. Mater. Sci: Mater. Electron., 32, 18451-18456(2021); DOI: 10.1007/s10854-021-06225-6.
  2. Influence of quinoline derivatives in I/I3− redox electrolyte solution on the performance of Ru(II)-dye-sensitized nanocrystalline TiO2 solar cell, H. Kusama et al., J. Photochem. Photobiol. A: Chem., 165, 157-163(2004); DOI: 10.1016/j.jphotochem.2004.03.013.
  3. Novel Ru(II) sensitizers bearing an unsymmetrical pyridine-quinoline hybrid ligand with extended π-conjugation: synthesis and application in dye-sensitized solar cells, G. Vougioukalakis et al., Dalton Trans., 42, 6582–6591(2013); DOI: 10.1039/c3dt33063j.
Return to the top