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Product Code B2301-5g
Price £76 ex. VAT

A tri-halogenated aniline building block

A synthesis intermediate for azo-dyes and macromolecules in application of solar cells, OLEDs, organic semiconductors, self-assemble molecular architectures and drug release

Specifications | MSDS | Literature and Reviews

4-Bromo-2,6-difluoroaniline (CAS number 67567-26-4) is an aniline derivative with a bromine at para-position and two fluorines at ortho-positions. The multiple substituents have different chemical reactivities, making 4-bromo-2,6-difluoroaniline a versatile building block in chemical synthesis. The bromo-substituent allows Pd-catalysed coupling reaction for expanding the size of the molecule. The amine group is used as a nucleophile in a chemical reaction, or it can also be oxidised to amine oxide to synthesize conjugated azo compounds. The fluoro-substitutes adjust the energy level of the molecular orbitals while they can undergo nucleophilic aromatic substitution for designing macromolecules.

A Pd-azobenzene complex based on 4-bromo-2,6-difluoroaniline has shown photo-switching properties. It can reversibly switch to two discrete self-assembled structures. A conjugated quasiplanar triarylamines synthesized from 4-bromo-2,6-difluoroaniline is used as hole-transporting material in perovskite solar cells and OLEDs.

Multiple functional groups

Multiple functional groups

For facile synthesis

Fluorinated building block

Fluorinated aniline building block

For semiconductors, solar cells and OLEDs

Worldwide shipping for 67567-26-4

Worldwide shipping

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High purity 67567-26-4

High purity

>98% High purity

General Information

CAS Number 67567-26-4
Chemical Formula C6H4F2NBr
Full Name 4-Bromo-2,6-difluoroaniline
Molecular Weight 208.01 g/mol
Synonyms 4-Bromo-2,6-difluorobenzenamine
Classification / Family Fluorinated building block, Amine building block, Azo-dyes, solar cells, OLEDs, semiconductors, macromolecules

Chemical Structure

4-Bromo-2,6-difluoroaniline chemical structure, CAS 67567-26-4
4-Bromo-2,6-difluoroaniline chemical structure, CAS 67567-26-4

Product Details

Purity 98%
Melting Point Tm = 63 – 65 °C
Appearance White powder

MSDS Documentation

4-Bromo-2,6-difluoroaniline4-Bromo-2,6-difluoroaniline MSDS Sheet

Literature and Reviews

  1. Partially oxygen-bridged triphenylamines with a quasiplanar structure as a key scaffold for hole-transporting materials, A. Wakamiya et al., J. Synth. Org. Chem. Jpn., 74(11), 1128–1135(2016); DOI: 10.5059/yukigoseikyokaishi.74.1128.
  2. Selective release of a potent anticancer agent from a supramolecular hydrogel using green light, J. Karcher et al., RSC Adv., 11, 8546(2021); DOI: 10.1039/d0ra08893e.
  3. Synthesis of novel phenoxyimine ligands containing a 2,6-difluoro-4-styrylaniline, B. Liu et al., J. Chem. Res., 35(3), 151–153(2011); DOI: 10.3184/174751911X12979306434042.

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