FREE shipping to on qualifying orders when you spend or more, processed by Ossila BV. All prices ex. VAT. Qualifying orders ship free worldwide! Fast, secure, and backed by the Ossila guarantee. It looks like you are visiting from , click to shop in or change country. Orders to the EU are processed by our EU subsidiary.
Join the Team About Ossila Contact Us Press |Log In Create Account| Worldwide, £ GBP   Flag

It looks like you are using an unsupported browser. You can still place orders by emailing us on info@ossila.com, but you may experience issues browsing our website. Please consider upgrading to a modern browser for better security and an improved browsing experience.

4-Fluoro-4′-methoxybenzophenone

CAS Number 345-89-1

Fluorinated Building Blocks, Monomers

4-Fluoro-4′-methoxybenzophenone CAS 345-89-1
Product Code B2891-5g
Price £90 ex. VAT
£ GBP

How to Order | Worldwide Shipping

A fluorinated benzophenone building block

Used in the synthesis of polyketone esters, fluorenes derivatives and photocatalysts

4-Fluoro-4′-methoxybenzophenone (CAS number 345-89-1) is a benzophenone building block with fluorine and methoxy groups on both para-positions. Benzophenone derivatives are photosensitive, thus, 4-fluoro-4′-methoxybenzophenone is applied as a photocatalyst for photochemical fluorination with sulfur hexafluoride as the fluorine source. The photocatalytic reaction is performed under a 365 nm UV radiation, resulting in a moderated 56% yield.

4-Fluoro-4′-methoxybenzophenone is also utilised in the preparation of fluorenone, a fluorene derivative with a ketone on the 9-position. Fluorenone finds widespread applications in pharmaceutical industry and organic electronics. The reaction involves a palladium-catalysed dehydrogenative cyclisation, yielding up to 90%.

Multiple functional groups

Multiple functional groups

For facile synthesis

Fluorinated building block

Fluorinated benzophenone building block

for organic electronics and photocatalytic chemistry research

Worldwide shipping for 345-89-1

Worldwide shipping

Quick and reliable shipping

High purity 345-89-1

High purity

>98% High purity

General Information

CAS Number 345-89-1
Chemical Formula C14H11FO2
Full Name (4-Fluorophenyl)(4-methoxyphenyl)methanone
Molecular Weight 230.23 g/mol
Synonyms N/A
Classification / Family Fluorinated building blocks, Benzophenone building blocks, Fluorenes, Polyketone esters, Photocatalysts

Chemical Structure

4-Fluoro-4′-methoxybenzophenone chemical structure, CAS 345-89-1.
4-Fluoro-4′-methoxybenzophenone chemical structure, CAS 345-89-1

Product Details

Purity 98%
Melting Point Tm = 96 °C
Appearance White crystals

MSDS Documentation

4-Fluoro-4′-methoxybenzophenone4-Fluoro-4′-methoxybenzophenone MSDS Sheet

Literature and Reviews

  1. Polymerisation and related reactions involving nucleophilic aromatic substitution. Part 1. The rates of reaction of substituted 4-halogenobenzophenones with the potassium salts of substituted 4-hydroxybenzophenones, J, Ridd et al., J. Chem. Soc., Perkin Trans. 2, 1729–1734(1988); DOI: 10.1039/P29880001729.
  2. Soluble telechelic polycondensation poly(ether ketones): synthesis and characterization, A. Benhalima et al., Macromol. Chem. Phys., 220, 1900234(2019); DOI: 10.1002/macp.201900234.
  3. A perspective on synthesis and applications of fluorenones, S. Patel et al., ChemistrySelect, 5, 10673–10691(2020); DOI: 10.1002/slct.202002695.
  4. Synthesis of glycosyl fluoride by photochemical fluorination with sulfur(VI) hexafluoride, S. Kim et al., Org. Lett., 23, 190–194(2021); DOI: 10.1021/acs.orglett.0c03915.
Return to the top