FREE shipping to on qualifying orders when you spend or more, processed by Ossila BV. All prices ex. VAT. Qualifying orders ship free worldwide! Fast, secure, and backed by the Ossila guarantee. It looks like you are visiting from , click to shop in or change country. Orders to the EU are processed by our EU subsidiary.

It looks like you are using an unsupported browser. You can still place orders by emailing us on info@ossila.com, but you may experience issues browsing our website. Please consider upgrading to a modern browser for better security and an improved browsing experience.


Product Code B1891-LT-500mg
Price £135 ex. VAT

A fluorinated heterocyclic building block

Used as a synthesis intermediate for APIs, DSSCs and sensors


Specifications | MSDS | Literature and Reviews


Bearing both bromo- and fluoro-substituents, 4-bromo-8-fluoroquinoline (CAS number 927800-38-2) is another useful intermediate for the preparation of active quinoline elements in drug discovery. Fluoroquinolines are typically used as active pharmaceutical ingredients (APIs) such as antibiotics. Additionally, 8-fluoroquinoline derivatives have also proven effective against insects, nematodes, and mites as agricultural chemicals. 4-Bromo-8-fluoroquinoline has multiple functional groups, which is an ideal candidate in substrate scopes for synthetic methodology studies.

This brominated building block can also be used as an end-capping material to extend the chromophore size of other chemicals through Pd-catalysed cross-coupling reactions. For example, it can enhance the fluorescent signal of cyclobarbital molecularly imprinted polymer for electrochemical sensing.

Multiple functional groups

Multiple functional groups

For facile synthesis

Fluorinated building block

Fluorinated quinoline building block

For drug discoveries, dyes, and solar cells

Worldwide shipping for 927800-38-2

Worldwide shipping

Quick and reliable shipping

High purity 927800-38-2

High purity

>98% High purity

General Information


CAS Number 927800-38-2
Chemical Formula C9H5BrFN
Full Name 4-Bromo-8-fluoroquinoline
Molecular Weight 226.05 g/mol
Synonyms N/A
Classification / Family Quinoline derivatives, Fluorinated building blocks, Heterocyclic building block, Dyes, DSSCs, Sensors, APIs

Chemical Structure


4-Bromo-8-fluoroquinoline chemical structure, CAS 927800-38-2
4-Bromo-8-fluoroquinoline chemical structure, CAS 927800-38-2

Product Details


Purity >98%
Melting Point Tm = 112 °C – 113 °C
Appearance White to light yellow powder/crystal

MSDS Documentation


4-Bromo-8-fluoroquinoline4-Bromo-8-fluoroquinoline MSDS Sheet

Literature and Reviews


  1. Tandem photoelectrochemical and photoredox catalysis for efficient and selective aryl halides functionalization by solar energy, Y.-J. Chen et al., Matter, 4, 2354–2366(2021); DOI: 10.1016/j.matt.2021.05.004.
  2. Bio-inspired imprinting materials for biomedical applications, H. Chen et al., Adv. Sci., 9, 2202038(2022); DOI: 10.1002/advs.202202038.
  3. Fluorinated quinolines: synthesis, properties and applications, G. Lipunova et al., Fluorine in Heterocyclic Chemistry, 2, 59-109(2015); DOI: 10.1007/978-3-319-04435-4_2.

Return to the top