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Product Code B1621-25g
Price £100 ex. VAT

A fluorinated β-diketone building block

Used as a synthesis intermediate for metal complexes, isoxazoles, pyrimidine and pyrazoles in application of OLEDs, displays, and drug discovery


Specifications | MSDS | Literature and Reviews


2-Furoyltrifluoroacetone (CAS number 326-90-9) is a derivative of β-diketone with a furan and a trifluoromethyl substituents. 2-Furoyltrifluoroacetone is directly applied as a ligand to the synthesis of luminescent terbium (Tb III) and lanthanide (Ln III) complexes that are used OLEDs and displays. The complexes have high quantum efficiency of 77% and long lifetime of 842 μs.

The furan of 2-Furoyltrifluoroacetone can be easily modified via Diels-Alder reactions (with electron deficient dienophiles) and electrophilic substitution.

The β-diketone (1,3-diketone) moiety is a precursor for many other heterocyclic compounds. 2-Furoyltrifluoroacetone reacts with hydrazine to form pyrazole, with hydroxylamine to form isoxazole, and with urea pyrimidine. The heterocyclic compounds are investigated as active pharmaceutical ingredients (APIs) for anticancer and anti-inflammatory drug discovery.

Multiple functional groups

Multiple functional groups

For facile synthesis

Fluorinated building block

Fluorinated diketone building block

For drug discovery, ligands, and OLEDs

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High purity 326-90-9

High purity

>98% High purity

General Information


CAS Number 326-90-9
Chemical Formula C8H5F3O3
Full Name 4,4,4-Trifluoro-1-(2-furyl)-1,3-butanedione
Molecular Weight 206.12 g/mol
Synonyms Perfluoroacetyl(2-furoyl)methane
Classification / Family Fluorinated building block, Heterocyclic building block, Diketone Derivatives, Pyrazoles, OLEDs, APIs, Display

Chemical Structure


2-Furoyltrifluoroacetone chemical structure, CAS 326-90-9
2-Furoyltrifluoroacetone chemical structure, CAS 326-90-9

Product Details


Purity 98%
Melting Point Tm = 19 °C – 21 °C
Boiling Point Tb= 203 °C at 760 mmHg
Relative Density 1.391 g/mL at 25 °C
Appearance Clear liquid

MSDS Documentation


2-Furoyltrifluoroacetone2-Furoyltrifluoroacetone MSDS Sheet

Literature and Reviews


  1. Luminescent Tb(III) complexes with Lewis bases for displays: Synthesis and spectral investigation, A. Hooda et al, Inorg. Chem. Commun., 151, 110583(2023); DOI: 10.1016/j.inoche.2023.110583.
  2. Anticancer activity of novel 3‐(furan‐2‐yl)pyrazolyl and 3‐(thiophen‐2‐yl)pyrazolyl hybrid chalcones: Synthesis and in vitro studies, M. Helmy et al., Arch. Pharm., 355, e2100381(2022); DOI: 10.1002/ardp.202100381.
  3. Exploration of photophysical behavior of lanthanide complex and its hybrids, S. Wankar et al., Spectrochim. Acta A Mol. Biomol., 254, 119629(2021); DOI: 10.1016/j.saa.2021.119629.
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