1,3,5-Tris(3-fluoro-4-formylphenyl)benzene

CAS Number 2088007-04-7

Carbaldehyde Monomers, Chemistry Building Blocks, COF Ligands, Fluorinated Building Blocks, Materials, Monomers, Porous Organic Frameworks

MSDS

1,3,5-Tris(3-fluoro-4-formylphenyl)benzene CAS 2088007-04-7

Covalent Organic Frameworks (COFs) Terphenyl Ligand

An aldehyde fluoro functionalised bridging ligand linker for COFs in application of fluorescence probe sensors, membrane, and detection of dopamine

Overview
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Trigonal 1,3,5-tris(3-fluoro-4-formylphenyl)benzene (TFFPB), CAS number 2088007-04-7, has a chemical structure of three 3-fluoro-4-formylphenyl groups sitting at the meta positions of a benzene ring. The aldehyde groups help to extend the structure to frameworks by forming covalent bonding and the fluoro-groups enhance the richness of the fluorine content of the targeted structures.

Constructed from 1,3,5-tris(4-aminophenyl) benzene (TPB) and 1,3,5-tri(3-fluoro-4-formylphenyl) benzene as the building elements at room temperature, porous covalent organic framework TPTF-COF is fluorine-rich, highly crystalline and thermally stable with rich functional group properties and large specific surface area of 1084.61 m²·g⁻¹.

Containing 1,3,5-tris(3-fluoro-4-formylphenyl)benzene nodes and acrylonitrile linkages, smart COF showed rapid pH-responsive absorption and fluorescence, high fluorescence quantum yield, and good crystallinity. It exhibited a 20% enhancement in fluorescence quantum yield and more rapid sensitivity of absorption and fluorescence under acid–base induction compared to its nonfluorinated counterpart.

MOF and COF ligands

Fluoride and aldehyde ligand for cross-linked COF networks

Worldwide shipping

Quick and reliable shipping

High purity

>98% High purity

Duo functionality

Enabling post-functionalisation

General Information

CAS Number	2088007-04-7
Chemical Formula	C₂₇H₁₅F₃O₃
Full Name	1,3,5-Tris(3-fluoro-4-formylphenyl)benzene
Molecular Weight	444.40 g/mol
Synonyms	TFFPB, 3,3''-Difluoro-5'-(3-fluoro-4-formylphenyl)-[1,1':3',1''-terphenyl]-4,4''-dicarbaldehyde
Classification / Family	Terphenyls, COF ligands, Fluorinated building blocks

Chemical Structure

Product Details

Purity	>98%
Melting Point	N/A
Appearance	White to yellow to orange powder/crystals

MSDS Documentation

1,3,5-Tris(3-fluoro-4-formylphenyl)benzene MSDS Sheet

Literature and Reviews

Acrylonitrile-Linked Covalent Organic Frameworks Enable Fast Stimulus-Responsive Fluorescence with High Quantum Yield via Fluorine Chemistry, M. Yang et al., Adv. Photonic Res., 3 (8), 2200008 (2022); DOI: 10.1002/adpr.202200008.
Fluorine-Containing Covalent Organic Frameworks: Synthesis and Application, W. Li et al., Macromol. Rapid Commun., 44 (11), 2200778 (2023); DOI: 10.1002/marc.202200778.
Fabrication of high-crystallinity covalent organic framework and its nylon based membrane: Application in the enrichment and interception of dyes, J. Wong et al., J. Environ. Chem. Eng., 11, 110989 (2023); DOI: 10.1016/j.jece.2023.110989.
Covalent organic frameworks: an ideal platform for designing ordered materials and advanced applications, R. Liu et al., Chem. Soc. Rev., 50, 120 (2021); DOI: 10.1039/d0cs00620c.
Fluoro-Substituted Covalent Organic Framework Particles Anchored on TiO2 Nanotube Arrays for Photoelectrochemical Determination of Dopamine, C. Wang et al., ACS Appl. Nano Mater., 4 (9), 8801–8812 (2021); DOI: 10.1021/acsanm.1c01466.

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