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Product Code B3861-250mg
Price $113 ex. VAT

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Covalent Organic Frameworks (COFs) Pyrene Ligand

An ethynyl functional ligand linker for COFs in application of photocatalyst, fluorescent sensors and 2,4,6-trinitrophenol detection


1-Ethynylpyrene is consisted of pyrene with an ethynyl functional group at 1-position. 1-Ethynylpyrene is often featured as a fluorescent probe in MOFs and COFs.

Prepared by post-synthesis of UIO-66-NH2 via an efficient click reaction with 1-ethynylpyrene, highly fluorescent UIO-66-Py-MOF was employed for 2,4,6-trinitrophenol (TNP) detection with significantly enhanced fluorescence intensity. It showed great selectivity and sensitivity for sensing TNP in solution via the fluorescence quenching mechanism. The UIO-66-Py showed an 85% fluorescence quenching efficiency with 0.203 mM TNP and low detection limit of 4.5 x 10−7 M.

Highly organized helical π-stacked arrangement of 1-ethynylpyrene moieties along the major groove of duplex DNA can be achieved should more than three chromophores be synthetically incorporated adjacent to each other.

MOF and COF ligands

MOF and COF ligands

Ethyne ligand for end-capping COF networks

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High purity 34993-56-1

High purity

>98% High purity

Facile reactions

Facile reactions

Readily for click reaction and Sonogashira reaction

General Information

CAS Number 34993-56-1
Chemical Formula C18H10
Full Name 1-Ethynylpyrene
Molecular Weight 226.28 g/mol
Synonyms Pyrenylacetylene
Classification / Family Pyrenes, COF ligands

Chemical Structure

34993-56-1 - 1-ethynylpyrene chemical structure
1-Ethynylpyrene Chemical Structure, 34993-56-1

Product Details

Purity >98%
Melting Point 117 °C
Appearance Dark grey powder/crystals

MSDS Documentation

34993-56-1 - 1-ethynylpyrene1-Ethynylpyrene MSDS Sheet

Literature and Reviews

  1. A highly fluorescent metal organic framework probe for 2,4,6-trinitrophenol detection via post-synthetic modification of UIO-66-NH2, Y. Tang et al., Dyes Pigm., 167, 10-15 (2019); DOI: 10.1016/j.dyepig.2019.03.055.
  2. DNA as a supramolecular scaffold for the helical arrangement of a stack of 1-ethynylpyrene chromophores, J. Barbaric et al., Org. Biomol. Chem., 4, 2088-2090 (2006); DOI: 10.1039/B605251G.
  3. Synthesis, characterization and optical properties of a series of copolymers bearing 1-ethynylpyrene and ethynylbenzene units, P. Porcu et al., MRS Advances, 5 (62); 3215 - 3225 (2020); DOI: 10.1557/adv.2020.428.
  4. Ethynylpyrene Linked Benzocrown Ethers as Fluorescent Sensors for Metal Ions, H. Maeda et al., Photochem. Photobiol., 95 (3), 762-772 (2019); DOI: 10.1111/php.13071.
  5. Post-exfoliation functionalisation of metal–organic framework nanosheets via click chemistry, J. Nicks et al., Nanoscale, 14, 6220-6227 (2022); DOI: 10.1039/D2NR00346E.
  6. Efficient Photoinduced Electron Transfer from Pyrene-o-Carborane Heterojunction to Selenoviologen for Enhanced Photocatalytic Hydrogen Evolution and Reduction of Alkynes, X. Yang et al., Adv. Sci., 9 (5), 2101652 (2022); DOI: 10.1002/advs.202101652.

To the best of our knowledge the information provided here is accurate. The values provided are typical at the time of manufacture and may vary over time and from batch to batch. Products may have minor cosmetic differences (e.g. to the branding) compared to the photos on our website. All products are for laboratory and research and development use only.

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