FREE shipping to on qualifying orders when you spend or more, processed by Ossila BV. All prices ex. VAT. Qualifying orders ship free worldwide! Fast, secure, and backed by the Ossila guarantee. It looks like you are visiting from , click to shop in or change country. Orders to the EU are processed by our EU subsidiary.

It looks like you are using an unsupported browser. You can still place orders by emailing us on info@ossila.com, but you may experience issues browsing our website. Please consider upgrading to a modern browser for better security and an improved browsing experience.

1,2,4,5-Tetrakis(4-formylphenyl)benzene

CAS Number 883835-33-4

Carbaldehyde Monomers, Chemistry Building Blocks, COF Ligands, Materials


Product Code B3771-1g
Price $150 ex. VAT

Quality assured

Expert support

Volume discounts

Worldwide shipping

Fast and secure


Covalent Organic Frameworks (COFs) Terphenyl Ligand

A formyl functional ligand linker for COFs in application of iodine uptake, photocatalytic hydrogen evolution (PHE), high-performance supercapacitors and heterogeneous catalysis


1,2,4,5-Tetrakis(4-formylphenyl)benzene (TFPB) is a cross-like terphenyl linker with four 4-formylphenyl functional groups attached to a benzene ring at 1,2,4,5-positions.

Constructed by the condensation reaction between 2,5-diaminobenzene-1,4-dithiol (DABDT) and 1,2,4,5-tetrakis-(4-formylphenyl)benzene, thiol-decorated covalent organic framework SH-COF-2 showed a high surface area of 227 m2 g−1 and enhanced electrochemical performance with a capacitance of 118 mF cm−2 and a capacitance retention >95% after 1000 cycles.

Highly conjugated two-dimensional covalent organic framework TFPB-PyTTA-COF, alternating 4,4',4'',4'''-(pyrene-1,3,6,8-tetrayl)tetraaniline (PyTTA) as the nodes and 1,2,4,5-tetrakis(4-formylphenyl)benzene as the bridging linker units, possessed high chemical and physical stability. TFPB-PyTTA-COF exhibited an excellent iodine uptake value of up to 5.6 g g−1, superior to most reported COF-based adsorbents for the adsorption of iodine.

COF-TPE-TPB-B, obtained via a [4 + 2] pathway with unreacted dangling formyl groups from the monomers TFPB and 1,1,2,2-tetra(4-aminophenyl)ethylene (TPE-NH2), exhibited photocatalytic hydrogen evolution (PHE) activity with improved hydrophilicity and better charge separation and transportation.

MOF and COF ligands

MOF and COF ligands

Aldehyde ligand for cross-linked COF networks

Worldwide shipping for 883835-33-4

Worldwide shipping

Quick and reliable shipping

High purity 883835-33-4

High purity

>98% High purity

Facile reactions

Facile reactions

Aldehyde possesses excellent reactivity

General Information

CAS Number 883835-33-4
Chemical Formula C34H22O4
Full Name 1,2,4,5-Tetrakis(4-formylphenyl)benzene
Molecular Weight 494.54 g/mol
Synonyms TFPB, 4-[2,4,5-Tris(4-formylphenyl)phenyl]benzaldehyde, [1,1:2,1-Terphenyl]-4,4-dicarboxaldehyde,4,5-bis(4-formylphenyl)-
Classification / Family Terphenyl, COF ligands

Chemical Structure

883835-33-4 - 1,2,4,5-tetrakis(4-formylphenyl)benzene chemical structure chemical structure
1,2,4,5-tetrakis(4-formylphenyl)benzene (TFPB) Chemical Structure, 883835-33-4

Product Details

Purity >98%
Melting Point 152°C ~ 156 °C
Appearance White or off-white powder/crystals

MSDS Documentation

883835-33-4 - 1,2,4,5-tetrakis(4-formylphenyl)benzene1,2,4,5-tetrakis(4-formylphenyl)benzene MSDS Sheet

Literature and Reviews

  1. Thiol-decorated covalent organic frameworks as multifunctional materials for high-performance supercapacitors and heterogeneous catalysis, D. Pakulski et al., J. Mater. Chem. A, 10, 16685-16696 (2022); DOI: 10.1039/D2TA03867F.
  2. Synthesis of a magnetic covalent organic framework as sorbents for solid-phase extraction of aflatoxins in food prior to quantification by liquid chromatography-mass spectrometry, L. Li et al., Food Chem., 387, 132821 (2022); DOI: 10.1016/j.foodchem.2022.132821.
  3. Platinum Nanoparticles Uniformly Dispersed on Covalent Organic Framework Supports for Selective Synthesis of Secondary Amines, N. Wang et al., ChemCatChem, 14 (5), e202101587 (2022); DOI: 10.1002/cctc.202101587.
  4. Highly Conjugated Two-dimensional Covalent Organic Frameworks for Efficient Iodine Uptake, M. Zhou et al., Chem. Asian J., 17 (15), e202200358 (2022); DOI: 10.1002/asia.202200358.
  5. Construction of Covalent Organic Frameworks with Partly Condensed Networks for Photocatalytic Hydrogen Evolution, C. Gao et al., ACS Appl. Energy Mater., 6 (18), 9427–9433 (2023); DOI: 10.1021/acsaem.3c01379.

To the best of our knowledge the information provided here is accurate. The values provided are typical at the time of manufacture and may vary over time and from batch to batch. Products may have minor cosmetic differences (e.g. to the branding) compared to the photos on our website. All products are for laboratory and research and development use only.

Return to the top