Hexa(4-formylphenyl)benzene

CAS Number 1862220-96-9

Carbaldehyde Monomers, Chemistry Building Blocks, COF Ligands, Materials, Porous Organic Frameworks

Hexa(4-formylphenyl)benzene CAS 1862220-96-9

Covalent organic frameworks (COFs) hexaphenylbenzene ligand

a C₆ symmetric ligand for synthesising controllable microporous COFs

Overview
Related Products

Hexa(4-formylphenyl)benzene (CAS number 1862220-96-9) is a ligand featuring a hexaphenylbenzene core and six aldehyde groups. Hexa(4-formylphenyl)benzene is a C₆ rotational symmetric ligand. This ligand is used in the construction of 2D COFs with various tiling topologies, including triangular, rhombille, and kagome, depending on the choice of linkers used in the reaction. The resulting 2D COFs have controllable pore sizes, offering short molecular diffusion length and facilitating host-guest interactions for drug delivery.

A COF with azine linkages can be prepared from hexa(4-formylphenyl)benzene and hydrazine. The resulting COF has high surface area exceeding 1200 m²/g, with an average pore size of 1 nm. It also demonstrates excellent performance of CO₂ and methane uptakes, with capacities of 20 wt% and 2.3 wt%, respectively.

Facile reactions

Aldehyde possesses excellent reactivity

High Purity

>98% Purity

Worldwide shipping

Quick and reliable shipping

MOF and COF ligands

Aldehyde ligand for cross-linked COF networks

General Information

CAS Number	1862220-96-9
Chemical Formula	C₄₈H₃₀O₆
Full Name	3',4',5',6'-Tetrakis(4-formylphenyl)-[1,1'2',1''-terphenyl]-4,4''-dicarbaldehyde
Molecular Weight	702.75 g/mol
Synonyms	Hexa(4-formylphenyl)benzene, HFBP, 4-[2,3,4,5,6-pentakis(4-formylphenyl)phenyl]benzaldehyde
Classification / Family	Hexaphenylbenzenes, COFs, Aldehyde ligands, Porous, CO₂ sorption, Drug delivery

Chemical Structure

Product Details

Purity	98%
Melting Point	N/A
Appearance	White powder

MSDS Documentation

Hexa(4-formylphenyl)benzene MSDS Sheet

Literature and Reviews

An azine-linked hexaphenylbenzene based covalent organic framework, S. Alahakoon et al., Chem. Commun., 52, 2843–2845 (2016); DOI: 10.1039/C5CC10408D.
Rational design of two-dimensional covalent tilings using a C₆-symmetric building block via on-surface Schiff base reaction, C. Lu et al., Chem. Commun., 55, 1326–1329 (2019); DOI: 10.1039/C8CC08801B.
Isoreticular series of two-dimensional covalent organic frameworks with the kgd topology and controllable micropores, L. Li et al., J. Am. Chem. Soc., 144 (14), 6475–6482 (2022); DOI: 10.1021/jacs.2c01199.
Three-dimensional covalent organic frameworks with the she topology, X. Xu et al., J. Am. Chem. Soc., 144 (40), 18511–18517 (2022); DOI: 10.1021/jacs.2c07733.
Covalent organic frameworks: a materials platform for structural and functional designs, N. Huang et al., Nat. Rev. Mater., 1, 16068 (2016); DOI: 10.1038/natrevmats.2016.68.

Related Products

We stock a wide range of COF ligands available to purchase online. Please contact us if you cannot find what you are looking for.

Benzene-1,3,5-tricarbohydrazide

£60
Price £30

1,3,5-Tris(4-cyanophenyl)benzene

£85
From £43

4',4''',4'''''-(1,3,5-triazine-2,4,6-triyl)tris([1,1'-biphenyl]-4-amine)

£80
From £40

1,3,6,8-Tetrakis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrene

£100
From £50

1,3,5-Tris[4-amino(1,1-biphenyl-4-yl)]benzene

£80
From £40

4',4''',4'''''-(1,3,5-Triazine-2,4,6-triyl)tris([1,1'-biphenyl]-4-carbaldehyde)

£70
From £35

[1,1':4',1'':4'',1'''-Quaterphenyl]-4,4'''-diamine

£100
From £50

5''-(4'-Formyl-[1,1'-biphenyl]-4-yl)-[1,1':4',1'':3'',1''':4''',1''''-quinquephenyl]-4,4''''-dicarbaldehyde

£100
From £50

4',4''',4''''',4'''''''-(Ethene-1,1,2,2-tetrayl)tetrakis([1,1'-biphenyl]-4-carbaldehyde)

£60
From £30

[1,1':3',1''-Terphenyl]-3,3'',5,5''-tetracarbaldehyde

£100
From £50

4',5'-Bis(4-aminophenyl)-[1,1':2',1''-terphenyl]-4,4''-diamine

£60
From £30

Tris[4-(5-formyl-2-thienyl)phenyl]amine

£80
From £40

4,4',4''-(Benzene-1,3,5-triyltris(ethyne-2,1-diyl))trianiline

£100
From £50

5,5',5''-(Benzene-1,3,5-triyl)tripicolinaldehyde

£120
From £60

2,9-Bis[p-(formyl)phenyl]-1,10-phenanthroline

£140
From £70

1,3,5-Tris(4-aminophenyl)benzene

£60
From £30

1,1,2,2-Tetrakis(4-ethynylphenyl)ethene

£120
From £60

AB-TFMB

From £90

1,2,3,4-Butanetetracarboxylic dianhydride (BDA)

£110
From £55

4,4'-(Hexafluoroisopropylidene)diphthalic anhydride (6FDA)

From £90

1,2,4,5-cyclohexanetetracarboxylic dianhydride (HPMDA)

£76
From £38

4,4'-(4,4'-isopropylidenediphenoxy)bis-(phthalic anhydride) (BPADA)

From £76

4,4'-Oxydiphthalic anhydride (ODPA)

£76
From £38

3,3',4,4'-Benzophenonetetracarboxylic dianhydride (BTDA)

£76
From £38

9,9-Bis(4-aminophenyl)fluorene (FDA)

From £100

Bicyclo(2.2.2)oct-7-ene-2,3,5,6-tetracarboxylic acid dianhydride (COeDA)

From £110

1,2,4,5-Tetra((4-aminophenyl)ethynyl)benzene

£110
From £55

4,4',4'',4'''-(Pyrene-1,3,6,8-tetrayl)tetraaniline

£65
From £33

[1,1':4',1''-Terphenyl]-4,4''-diacetonitrile

£65
From £33

4,4'-Biphenyldiacetonitrile

£60
From £30

2,4,6-Tris[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1,3,5-triazine

£60
From £30

1,3,6,8-Tetraethynyl-9H-carbazole

£100
Price £50

4,4',4''-(pyridine-2,4,6-triyl)tribenzaldehyde

£85
From £43

2',5'-Dimethoxy-[1,1':4',1''-terphenyl]-4,4''-dicarbaldehyde

£85
From £43

1,3,6,8-Tetrakis(4-formylphenyl)pyrene

£65
From £33

1,3,5-Tris[(4-phenylboronic acid)]benzene

£85
From £43

1,3,5-Tris(3-fluoro-4-formylphenyl)benzene

£80
From £40

5'-(4-Formylphenyl)-2',4',6'-trimethyl-[1,1':3',1''-terphenyl]-4,4''-dicarbaldehyde

£75
From £38

4,4'-(Benzo[c][1,2,5]thiadiazole-4,7-diyl)dianiline

£90
From £45

4,4'-(Benzo[c][1,2,5]thiadiazole-4,7-diyl)dibenzaldehyde

£80
From £40

4-(1,2,2-Triphenylvinyl)benzaldehyde

£80
From £40

1-Ethynylpyrene

£90
From £45

9,10-Bis(4-formylphenyl)anthracene

£70
From £35

4,4'-Diethynyl-1,1'-biphenyl

£70
From £35

4,4',4''-(Benzene-1,3,5-triyltris(ethyne-2,1-diyl))tribenzaldehyde

£110
From £55

4,4''-p-Terphenyldicarboxaldehyde

£85
From £43

5-(4-(Diphenylamino)phenyl)thiophene-2-carbaldehyde

£100
From £50

4',4''',4'''''-Nitrilotris([1,1'-biphenyl]-4-carbaldehyde)

£90
From £45

1,3,5-Tris(4-ethynylphenyl)benzene

£110
From £55

2,4,6-Tris(4-ethynylphenyl)-1,3,5-triazine

£110
From £55

1,2,4,5-Tetrakis(4-formylphenyl)benzene

£120
From £60

2,3-Bis(4-bromophenyl)fumaronitrile

£150
From £75

3,5-Diformylphenylboronic acid

£150
From £75

((1,3,5-Triazine-2,4,6-triyl)tris(benzene-4,1-diyl))triboronic acid

£120
From £60

4,4',4'',4'''-(Pyrene-1,3,6,8-tetrayltetrakis(ethyne-2,1-diyl))tetraaniline

£100
From £50

[1,1'-Biphenyl]-3,3',5,5'-tetracarbaldehyde

£100
From £50

Tetrakis(4-formylphenyl)silane

£100
From £50

Tris(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)amine

£70
From £35

5'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,1':3',1''-terphenyl]-4,4''-diamine

£160
From £80

5'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,1':3',1''-terphenyl]-4,4''-dicarbaldehyde

£160
From £80

4,4'-((4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)azanediyl)dibenzaldehyde

£150
From £75

2,5-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)terephthalaldehyde

£160
From £80

1,3,5-Tris(4-formyl-3-hydroxyphenyl)benzene

£160
From £80

5,5'-(Ethyne-1,2-diyl)diisophthalaldehyde

£160
From £80

3,3'-Dihydroxy-[1,1'-biphenyl]-4,4'-dicarbaldehyde

£125
From £63

1,3,5-Tris(4-formylphenyl)benzene

£60
From £30

4,4'-(2,2-Diphenylethene-1,1-diyl)dibenzaldehyde

£150
From £75

4,4'-(Ethyne-1,2-diyl)dibenzaldehyde

£100
From £50

2,2'-(5'-(4-(Cyanomethyl)phenyl)-[1,1':3',1''-terphenyl]-4,4''-diyl)diacetonitrile

£125
From £63

Benzene-1,3,5-triyltriboronic acid

£150
From £75

[3,3-Bipyridine]-6,6-dicarboxaldehyde

£148
From £74

Tris(4-ethynylphenyl)amine

£150
From £75

5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isophthalaldehyde

£100
From £50

2,5-Diethoxyterephthalohydrazide

£76
From £38

[1,1'-Biphenyl]-3,4',5-tricarbaldehyde

£133
From £67

4,4',4'',4'''-(Ethene-1,1,2,2-tetrayl)tetrabenzaldehyde

£175
From £88

p-6FDAP

From £110

4,4'-Bis(4-aminophenoxy)biphenyl (BAPB)

£76
From £38

4,4'-Bis(3-aminophenoxy)biphenyl (43BAPOBP)

From £90

4,4'-(1,3-Phenylenedioxy)dianiline (TPE-R)

From £70

3,4'-Oxydianiline (3,4'-ODA)

£90
From £45

2,2-Bis[4-(4-aminophenoxy)phenyl]propane (BAPP)

£56
From £28

2,2-Bis[4-(4-aminophenoxy)phenyl]hexafluoropropane (4-BDAF)

From £76

2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane (6FAP)

£76
From £38

2,2-Bis(3-(3-aminobenzoylamino)-4-hydroxyphenyl)hexafluoropropane (m-6FDAP)

From £130

2,2'-Dimethyl[1,1'-biphenyl]-4,4'-diamine

£76
From £38

2,2'-Bis(trifluoromethyl)benzidine (TFMB)

From £76

2,2'-Bis(trifluoromethyl)-4,4'-diaminodiphenyl ether (6FODA)

From £76

1,4-Bis(4-amino-2-trifluoromethylphenoxy)benzene (6FAPB)

£76
From £38

1,4-Bis(4-aminophenoxy)benzene (TPE-Q)

£76
From £38