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CAS Number 1136292-71-1

Chemistry Building Blocks, COF Ligands, MOF Ligands, Porous Organic Frameworks

Product Code B3501-500mg
Price $95 ex. VAT

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Covalent organic frameworks (COFs) terephthalohydrazide ligand

serves as a linker for COFs enabling applications including photocatalytic hydrogen evolution, CO2 sorption, sensors and filtration membranes

2,5-Diethoxyterephthalohydrazide (CAS number 1136292-71-1), is a para-diethoxybenzene substituted with two carbohydrazide at 1-, 4-potition. 2,5-Diethoxyterephthalohydrazide is well-known for its synthesis of COF-42 with 1,3,5-triformylbenzene. COF-42 is chemically robust due to its hydrazide linkers and is widely employed as the platform for photocatalytic hydrogen evolution. When 2,5-diethoxyterephthalohydrazide reacts with metalated-porphyrinic aldehydes, it produces 2D COFs (MPor-DETH-COFs, M: Zn, Ni, Co). These MPhor-DETH-COFs exhibit photocurrent of up to 0.9 μA/cm2 and an average hydrogen evolution rate up to 413 μmol/g/h.

COFs synthesised from 2,5-diethoxyterephthalohydrazide and triformylbenzene derivatives feature large amount of amines in the network making it favourable for capturing CO2. These COFs show a high surface area of 2336 m2/g and CO2 uptake capacities ranging from 1.14-2.66 mmol/g.

Facile reactions

Facile reactions

Hydrazide possesses excellent reactivity

High Purity 1136292-71-1

High Purity

>98% Purity

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MOF and COF ligands

MOF and COF ligands

hydrazide ligand for cross-linked COF networks

General Information

CAS Number 1136292-71-1
Chemical Formula C12H18N4O4
Full Name 2,5-Diethoxyterephthalohydrazide
Molecular Weight 282.30 g/mol
Synonyms 2,5-diethoxybenzene-1,4-dicarbohydrazide, DETH
Classification / Family Terephthalohydrazides, Hydrazide ligands, COFs ligands, MOF ligands, Hydrogen evolution, CO2 sorption

Chemical Structure

2,5-Diethoxyterephthalohydrazide chemical structure, CAS 1136292-71-1
2,5-Diethoxyterephthalohydrazide chemical structure, CAS 1136292-71-1

Product Details

Purity 98%
Melting Point N/A
Appearance White powder

MSDS Documentation

2,5-Diethoxyterephthalohydrazide2,5-Diethoxyterephthalohydrazide MSDS Sheet

Literature and Reviews

  1. Rational design of covalent cobaloxime-covalent organic framework hybrids for enhanced photocatalytic hydrogen evolution, K. Gottschling et al., J. Am. Chem. Soc., 142, 12146–12156 (2020); DOI: 10.1021/jacs.0c02155.
  2. Molecular insights into carbon dioxide sorption in hydrazone-based covalent organic frameworks with tertiary amine moieties, K. Gottschling et al., Chem. Mater. ,31, 1946–1955 (2019); DOI: 10.1021/acs.chemmater.8b04643.
  3. Light-emitting covalent organic frameworks: fluorescence improving via pinpoint surgery and selective switch-on sensing of anions, Z. Li et al., J. Am. Chem. Soc., 140 (39), 12374–12377 (2018); DOI: 10.1021/jacs.8b08380.
  4. Tuning the activity-stability balance of photocatalytic organic materials for oxidative coupling reactions, A. Jiménez-Almarza et al., ACS Appl. Mater. Interfaces, 14, 16258–16268 (2022); DOI: 10.1021/acsami.2c01646.
  5. Rational design of isostructural 2D porphyrin-based covalent organic frameworks for tunable photocatalytic hydrogen evolution, R. Chen et al., Nat. Comm., 12, 1354 (2021); DOI: 10.1038/s41467-021-21527-3.
  6. Microporous organic nanotube assisted design of high performance nanofiltration membranes, S. Han et al., 13, 7954 (2022); DOI: 10.1038/s41467-022-35681-9.

To the best of our knowledge the information provided here is accurate. The values provided are typical at the time of manufacture and may vary over time and from batch to batch. Products may have minor cosmetic differences (e.g. to the branding) compared to the photos on our website. All products are for laboratory and research and development use only.

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