2,5-Diethoxyterephthalohydrazide

CAS Number 1136292-71-1

Chemistry Building Blocks, COF Ligands, Materials, Porous Organic Frameworks

2,5-Diethoxyterephthalohydrazide CAS 1136292-71-1

Covalent organic frameworks (COFs) terephthalohydrazide ligand

serves as a linker for COFs enabling applications including photocatalytic hydrogen evolution, CO₂ sorption, sensors and filtration membranes

Overview
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2,5-Diethoxyterephthalohydrazide (CAS number 1136292-71-1), is a para-diethoxybenzene substituted with two carbohydrazide at 1-, 4-potition. 2,5-Diethoxyterephthalohydrazide is well-known for its synthesis of COF-42 with 1,3,5-triformylbenzene. COF-42 is chemically robust due to its hydrazide linkers and is widely employed as the platform for photocatalytic hydrogen evolution. When 2,5-diethoxyterephthalohydrazide reacts with metalated-porphyrinic aldehydes, it produces 2D COFs (MPor-DETH-COFs, M: Zn, Ni, Co). These MPhor-DETH-COFs exhibit photocurrent of up to 0.9 μA/cm² and an average hydrogen evolution rate up to 413 μmol/g/h.

COFs synthesised from 2,5-diethoxyterephthalohydrazide and triformylbenzene derivatives feature large amount of amines in the network making it favourable for capturing CO₂. These COFs show a high surface area of 2336 m²/g and CO₂ uptake capacities ranging from 1.14-2.66 mmol/g.

Facile reactions

Hydrazide possesses excellent reactivity

High Purity

>98% Purity

Worldwide shipping

Quick and reliable shipping

MOF and COF ligands

hydrazide ligand for cross-linked COF networks

General Information

CAS Number	1136292-71-1
Chemical Formula	C₁₂H₁₈N₄O₄
Full Name	2,5-Diethoxyterephthalohydrazide
Molecular Weight	282.30 g/mol
Synonyms	2,5-diethoxybenzene-1,4-dicarbohydrazide, DETH
Classification / Family	Terephthalohydrazides, Hydrazide ligands, COFs ligands, MOF ligands, Hydrogen evolution, CO₂ sorption

Chemical Structure

Product Details

Purity	98%
Melting Point	N/A
Appearance	White powder

MSDS Documentation

2,5-Diethoxyterephthalohydrazide MSDS Sheet

Literature and Reviews

Rational design of covalent cobaloxime-covalent organic framework hybrids for enhanced photocatalytic hydrogen evolution, K. Gottschling et al., J. Am. Chem. Soc., 142, 12146–12156 (2020); DOI: 10.1021/jacs.0c02155.
Molecular insights into carbon dioxide sorption in hydrazone-based covalent organic frameworks with tertiary amine moieties, K. Gottschling et al., Chem. Mater. ,31, 1946–1955 (2019); DOI: 10.1021/acs.chemmater.8b04643.
Light-emitting covalent organic frameworks: fluorescence improving via pinpoint surgery and selective switch-on sensing of anions, Z. Li et al., J. Am. Chem. Soc., 140 (39), 12374–12377 (2018); DOI: 10.1021/jacs.8b08380.
Tuning the activity-stability balance of photocatalytic organic materials for oxidative coupling reactions, A. Jiménez-Almarza et al., ACS Appl. Mater. Interfaces, 14, 16258–16268 (2022); DOI: 10.1021/acsami.2c01646.
Rational design of isostructural 2D porphyrin-based covalent organic frameworks for tunable photocatalytic hydrogen evolution, R. Chen et al., Nat. Comm., 12, 1354 (2021); DOI: 10.1038/s41467-021-21527-3.
Microporous organic nanotube assisted design of high performance nanofiltration membranes, S. Han et al., 13, 7954 (2022); DOI: 10.1038/s41467-022-35681-9.

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