FREE shipping to on qualifying orders when you spend or more, processed by Ossila BV. All prices ex. VAT. Qualifying orders ship free worldwide! Fast, secure, and backed by the Ossila guarantee. It looks like you are visiting from , click to shop in or change country. Orders to the EU are processed by our EU subsidiary.

It looks like you are using an unsupported browser. You can still place orders by emailing us on info@ossila.com, but you may experience issues browsing our website. Please consider upgrading to a modern browser for better security and an improved browsing experience.

1,3,5-Tris(4-cyanophenyl)benzene

CAS Number 382137-78-2

COF Ligands, Materials, Porous Organic Frameworks


Product Code B4651-1g
Price £68 ex. VAT

Covalent organic frameworks (COFs) Terphenyl ligand

Triangular carbonitrile bridging ligand for the synthesis of COFs in application of photocatalyst for hydrogen evolution reactions (HERs), photo-induced atom transfer radical polymerization, and iodine sensing


Specifications | MSDS | Literature and Reviews


1,3,5-Tris(4-cyanophenyl)benzene (TCPB) is triangular shaped with three 4-cyanophenyl groups attached to a central benzene at 1,3,5-positions. 1,3,5-Tris(4-cyanophenyl)benzene is a great precursor for synthesising  nitrogen rich triazine based COFs as photocatalysts for hydrogen evolution reactions (HERs).

s-Tetrazine-based porous organic polymer TPBTz, an excellent adsorbent for capturing iodine prepared by the polymerization of 1,3,5-tris(4-cyanophenyl)benzene and hydrazine hydrate catalysed by sulfur powder, shows high selective and sensitive sensing of iodine and picric acid in real-time as fluorescent sensor. TPBTz exhibits extremely high sensitivity for iodine with KSV of 1.70 × 105 L mol−1 and the limit of detection of 1.76 × 10–11 mol L−1.

MOF and COF ligands

MOF and COF ligands

Triazine ligand for cross-linked COF networks

Worldwide shipping for 910231-21-9

Worldwide shipping

Quick and reliable shipping

High purity 910231-21-9

High purity

>98% High purity

Facile reactions

Facile reactions

Readily polycondensation cross-coupling reactions  to form COF networks

General Information


CAS Number 382137-78-2
Chemical Formula C27H15N3
Full Name 1,3,5-Tris(4-cyanophenyl)benzene
Molecular Weight 381.43 g/mol
Synonyms TCPB, 5'-(4-Cyanophenyl)-[1,1':3',1''-terphenyl]-4,4''-dicarbonitrile
Classification / Family COFs, Terphenyls, Carbonitrile

Chemical Structure


382137-78-2 - 1,3,5-tris(4-cyanophenyl)benzene chemical structure
1,3,5-Tris(4-cyanophenyl)benzene (TCPB) Chemical Structure, CAS 382137-78-2

Product Details


Purity > 98%
Melting Point N/A
Appearance White to off-white powder/crystals


MSDS Documentation


382137-78-2 - 1,3,5-tris(4-cyanophenyl)benzene1,3,5-Tris(4-cyanophenyl)benzene MSDS Sheet

Literature and Reviews


  1. A General Strategy for Kilogram-Scale Preparation of Highly Crystalline Covalent Triazine Frameworks, T. Sun et al., Angew. Chem. Int. Ed., 134 (25), e202203327 (2022); DOI: 10.1002/ange.202203327.
  2. Probing the Thermodynamics of Moiré Patterns in Molecular Self-Assembly at the Liquid–Solid Interface, D. Cui et al., Chem. Mater. 2022, 34, 5, 2449–2457 (2022); DOI: 10.1021/acs.chemmater.2c00089.
  3. Tunable Covalent Triazine-Based Frameworks (CTF-0) for Visible-Light-Driven Hydrogen and Oxygen Generation from Water Splitting, D. Kong et al., ACS Catal., 9 (9), 7697–7707 (2019); DOI: 10.1021/acscatal.9b02195.
Return to the top