FREE shipping to on qualifying orders when you spend or more, processed by Ossila BV. All prices ex. VAT. Qualifying orders ship free worldwide! Fast, secure, and backed by the Ossila guarantee. It looks like you are visiting from , click to shop in or change country. Orders to the EU are processed by our EU subsidiary.

It looks like you are using an unsupported browser. You can still place orders by emailing us on info@ossila.com, but you may experience issues browsing our website. Please consider upgrading to a modern browser for better security and an improved browsing experience.

4,4'-(Ethyne-1,2-diyl)dibenzaldehyde

CAS Number 84907-55-1

Carbaldehyde Monomers, Chemistry Building Blocks, COF Ligands, Porous Organic Frameworks


Product Code B3571-500mg
Price $125 ex. VAT

Quality assured

Expert support

Volume discounts

Worldwide shipping

Fast and secure


Covalent organic frameworks (COFs) diphenylacetylene ligand

for the synthesis of porous COFs as biocatalysts and photocatalysts, and macromolecules as fluorescent dyes


4,4'-(Ethyne-1,2-diyl)dibenzaldehyde (CAS number 84907-55-1), is a diphenylacetylene derivative capped with two aldehyde functional groups. 4,4'-(Ethyne-1,2-diyl)dibenzaldehyde is employed for the preparation of an imine-linkage dual-pore COF with ethylenetetraaniline. The COF can immobilise lipase PS for enantioselectivity reaction of racemic secondary alcohols, showing 50% conversion over 80 minutes. Additionally, 4,4'-(ethyne-1,2-diyl)dibenzaldehyde reacts with trimethyltriazine to produce COFs that are used in photocatalytic reaction for H2O2 production (1.8 mmol h-1 g-1).

Other than COFs, 4,4'-(ethyne-1,2-diyl)dibenzaldehyde also finds application in the synthesis of fluorescent macromolecules with a fluorescence quantum yield of 32%. The synthesis of this ethynyl-linked boron dipyrromethene involves a Rothmund reaction between 4,4'-(ethyne-1,2-diyl)dibenzaldehyde and a pyrrole derivative, followed by boron complexation.

Facile reactions

Facile reactions

Aldehyde possesses excellent reactivity

High Purity 84907-55-1

High Purity

>98% Purity

Worldwide shipping for 84907-55-1

Worldwide shipping

Quick and reliable shipping

MOF and COF ligands

MOF and COF ligands

Aldehyde ligand for cross-linked COF networks

General Information

CAS Number 84907-55-1
Chemical Formula C16H10O2
Full Name 4,4'-(1,2-Ethynediyl)dibenzaldehyde
Molecular Weight 234.25 g/mol
Synonyms Di(4-formylphenyl)acetylene, Diphenylacetylene-4,4'-dicarbaldehyde, 4-[2-(4-formylphenyl)ethynyl]benzaldehyde, EDDA
Classification / Family Diphenylacetylenes, Dialdehyde ligands, COFs, Fluorescent dyes, Biocatalysis, photocatalysis

Chemical Structure

4,4'-(Ethyne-1,2-diyl)dibenzaldehyde chemical structure, CAS 84907-55-1.
4,4'-(Ethyne-1,2-diyl)dibenzaldehyde chemical structure, CAS 84907-55-1

Product Details

Purity 98%
Melting Point N/A
Appearance Yellow powder

MSDS Documentation

4,4'-(Ethyne-1,2-diyl)dibenzaldehyde4,4'-(Ethyne-1,2-diyl)dibenzaldehyde MSDS Sheet

Literature and Reviews

  1. Constructing synergistic triazine and acetylene cores in fully conjugated covalent organic frameworks for cascade photocatalytic H2O2 production, L. Zhai et al., Chem. Mater., 34(11), 5232–5240 (2022); DOI: 10.1021/acs.chemmater.2c00910.
  2. Tuning pore heterogeneity in covalent organic frameworks for enhanced enzyme accessibility and resistance against denaturants, Q. Sun et al., Adv. Mater., 31, 1900008 (2019); DOI: 10.1002/adma.201900008.
  3. Enzyme immobilization in covalent organic frameworks: strategies and applications in biocatalysis, F. Oliveira et al., ChemPlusChem, 85, 2051–2066 (2020); DOI: 10.1002/cplu.202000549.
  4. Poly(thiosemicarbazone)s by condensation of dithiosemicarbazides and dialdehydes, R. Nickisch et al., Macromolecules 2022, 55 (8), 3267–3275 (2022); DOI: 10.1021/acs.macromol.2c00409.
  5. Synthesis, spectroscopic properties, and computational study of (E,Z)-ethenyl and ethynyl-linked BODIPYs, G. Zhang et al., J. Phys. Chem. A, 122, 6256–6265 (2018); DOI: 10.1021/acs.jpca.8b05149.

To the best of our knowledge the information provided here is accurate. The values provided are typical at the time of manufacture and may vary over time and from batch to batch. Products may have minor cosmetic differences (e.g. to the branding) compared to the photos on our website. All products are for laboratory and research and development use only.

Return to the top