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2,2'-(5'-(4-(Cyanomethyl)phenyl)-[1,1':3',1''-terphenyl]-4,4''-diyl)diacetonitrile

CAS Number 2311888-44-3

Chemistry Building Blocks, COF Ligands, Porous Organic Frameworks


Product Code B3561-500mg
Price $157 ex. VAT

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Covalent organic frameworks (COFs) triphenylbenzene ligand

utilised to synthesised COFs for photocatalysis, optoelectronics and fluorescent dyes


2,2'-(5'-(4-(Cyanomethyl)phenyl)-[1,1':3',1''-terphenyl]-4,4''-diyl)diacetonitrile (CAS number 2311888-44-3), also known as 1,3,5-tris(4-cyanomethylphenyl)benzene, has a triphenylbenzene core substituted by three cyanomethyl groups. 2,2'-(5'-(4-(Cyanomethyl)phenyl)-[1,1':3',1''-terphenyl]-4,4''-diyl)diacetonitrile undergoes a Knoevenagel condensation reaction, in basic conditions, with di/trialdehyde substituted ligands to form phenylene vinylene COFs containing nitrile anchoring groups. The resulting COFs are fully conjugated and they exhibit photoluminescent quantum yield of 27% (and up to 33% with fluorinated aldehyde ligands). The nitrile anchoring groups can be further converted to carboxylic acids which can coordinate to metal centres to prepare COF-metal complexes.

The COFs synthesised from 2,2'-(5'-(4-(cyanomethyl)phenyl)-[1,1':3',1''-terphenyl]-4,4''-diyl)diacetonitrile has high crystallinity and good stability. These COFs are applied in the photocatalytic oxidation reaction, effectively converting boronic acid to alcohols under visible light.

Facile reactions

Facile reactions

Readily for Knoevenagel condensation reaction

High Purity 2311888-44-3

High Purity

>98% Purity

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MOF and COF ligands

MOF and COF ligands

Nitrile ligand for cross-linked COF networks

General Information

CAS Number 2311888-44-3
Chemical Formula C30H21N3
Full Name 2,2'-(5'-(4-(Cyanomethyl)phenyl)-[1,1':3',1''-terphenyl]-4,4''-diyl)diacetonitrile
Molecular Weight 423.52 g/mol
Synonyms 1,3,5-tris(4-cyanomethylphenyl)benzene, 2-[4-[3,5-Bis[4-(cyanomethyl)phenyl]phenyl]phenyl]acetonitrile, TCPB
Classification / Family Triphenylbenzenes, Benzylnitrile ligands, Benzyl cyanide ligands, COFs, Photocatalysis, Optoelectonics, Fluorescent dyes

Chemical Structure

2,2'-(5'-(4-(Cyanomethyl)phenyl)-[1,1':3',1''-terphenyl]-4,4''-diyl)diacetonitrile chemical structure, CAS 2311888-44-3.
2,2'-(5'-(4-(Cyanomethyl)phenyl)-[1,1':3',1''-terphenyl]-4,4''-diyl)diacetonitrile chemical structure, CAS 2311888-44-3

Product Details

Purity 98%
Melting Point N/A
Appearance Yellow powder

MSDS Documentation

2,2'-(5'-(4-(Cyanomethyl)phenyl)-[1,1':3',1''-terphenyl]-4,4''-diyl)diacetonitrile2,2'-(5'-(4-(Cyanomethyl)phenyl)-[1,1':3',1''-terphenyl]-4,4''-diyl)diacetonitrile MSDS Sheet

Literature and Reviews

  1. Fully sp2-carbon-linked crystalline two-dimensional conjugated polymers: insight into 2D poly(phenylenecyanovinylene) formation and their optoelectronic properties, D. Becker et al., Chem. Eur. J., 25, 6562 (2019); DOI: 10.1002/chem.201806385.
  2. Acrylonitrile-linked covalent organic frameworks enable fast stimulus-responsive fluorescence with high quantum yield via fluorine chemistry, M. Yang et al., Adv. Photonics Res., 3, 2200008 (2022); DOI: 10.1002/adpr.202200008.
  3. Nanoporous vinylene-linked 2D covalent organic frameworks for visible-light-driven aerobic oxidation, W. Wang et al., ACS Appl. Nano Mater., 6 (10), 8396–8403 (2023); DOI: 10.1021/acsanm.3c00691.
  4. Design and synthesis of a triazine-based sp2 carbon-conjugated covalent organic framework for blue light photocatalysis, F. Zhang et al., Small, 19 (38), 2302456 (2023); DOI: 10.1002/smll.202302456.

To the best of our knowledge the information provided here is accurate. The values provided are typical at the time of manufacture and may vary over time and from batch to batch. Products may have minor cosmetic differences (e.g. to the branding) compared to the photos on our website. All products are for laboratory and research and development use only.

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