4,4'-Biphenyldiacetonitrile

CAS Number 7255-83-6

Chemistry Building Blocks, COF Ligands, Materials, Porous Organic Frameworks

4,4'-Biphenyldiacetonitrile CAS 7255-83-6

Covalent Organic Frameworks (COFs) Biphenyl Ligand

An acetonitrile functionalised bridging ligand linker for COFs in application of visible light-induced hydrogen production and photocatalyst and biosensors

Overview
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4,4'-Biphenyldiacetonitrile, CAS number 7255-83-6, has a linear biphenyl linker with acetonitrile groups on both ends. 4,4'-Biphenyldiacetonitrile is commonly used in the preparation of microporous organic networks with aldehydes via the Knoevenagel condensation.

Prepared by the Knoevenagel condensation of tri(4-formylphenyl)amine with 4,4'-biphenyldiacetonitrile, visible light harvesting microporous COF showed visible light absorption in 400 – 530 nm and vivid emission at 542 nm. The COF/TiO₂–Pt composite exhibited promising activity and enhanced stability as a photocatalytic system for visible light-induced hydrogen production from water.

Olefin-linked chiral CCOF 18 with 2D layered tetragonal structure was obtained by Knoevenagel polycondensation of chiral tetrabenzaldehyde of dibinaphthyl-22-crown-6 with 4,4′-biphenyldiacetonitrile. Reduction of the olefin linkage of CCOF-18 produced C–C single bond linked framework CCOF-18-R, while retaining high crystallinity and porosity as well as high chemical stability in both strong acids and bases.

MOF and COF ligands

Nitrile ligand for cross-linked COF networks

Worldwide shipping

Quick and reliable shipping

High purity

>98% High purity

Facile reactions

Readily for Knoevenagel condensation reaction

General Information

CAS Number	7255-83-6
Chemical Formula	C₁₆H₁₂N₂
Full Name	4,4'-Biphenyldiacetonitrile
Molecular Weight	232.28 g/mol
Synonyms	BPDAN, 2,2'-([1,1'-Biphenyl]-4,4'-diyl)diacetonitrile, 2-[4'-(cyanomethyl)-[1,1'-biphenyl]-4-yl]acetonitrile
Classification / Family	Biphenyls, COF ligands, Acetonitriles

Chemical Structure

Product Details

Purity	>98%
Melting Point	N/A
Appearance	White to off-white powder/crystals

MSDS Documentation

4,4'-Biphenyldiacetonitrile MSDS Sheet

Literature and Reviews

Microporous organic nanorods with electronic push–pull skeletons for visible light-induced hydrogen evolution from water, J. Park et al., J. Mater. Chem. A, 2, 7656-7661 (2014); DOi: 10.1039/C4TA00989D.
Crystalline C—C and C═C Bond-Linked Chiral Covalent Organic Frameworks, C. yuan et al., J. Am. Chem. Soc., 143 (1), 369–381 (2021); DOI: 10.1021/jacs.0c11050.
Macrocycle-Based Porous Organic Polymers for Separation, Sensing, and Catalysis, Z. Li et al., Adv. Mater., 34 (6), 2107401 (2022); DOI: 10.1002/adma.202107401.
Macrocycle-Based Covalent Organic Frameworks, Y. Yuan et al., Adv. Mater., 35 (16), 2210952 (20230; DOI: 10.1002/adma.202210952.
Luminescent Covalent Organic Frameworks for Biosensing and Bioimaging Applications, J. Ma et al., Small, 18 (3), 2103516 (2022); DOI: 10.1002/smll.202103516.

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