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Product Code B2041-10g
Price $79 ex. VAT

An alicyclic dianhydride building block

For polyimides and polyesters synthesis to be applied as photochromic materials, proton conducting membranes, and bioimaging polymers

Specifications | MSDS | Literature and Reviews

1,2,4,5-Cyclohexanetetracarboxylic dianhydride (HPMDA, CAS number 2754-41-8) has a cyclohexane centre with two carboxylic anhydrides substituents sitting opposite to each other. HPMDA reacts with amines for polyimides or alternatively with alcohols for polyesters. The non-aromatic cyclohexane centre provides local excited state to the synthesized photochromic polyimides showing large contrast of the photo-switching effect (compared to fully aromatized polyimides). The polyimides derived from 1,2,4,5-cyclohexanetetracarboxylic dianhydride exhibit high proton conductivity (0.2 ± 0.01 S/cm at 298 K and 95% related humidity). Like other polyimides, the polyimides have excellent chemical and thermal resistance and are used in optical fibre claddings and substrates for microelectronics.

HPMDA can be used to synthesize polyesters that have four branches (dianhydride is hydrolysed to four carboxylic acids) for multiple functionalities, such as biodegradability, bioimaging and photoactivity.

General Information

CAS Number 2754-41-8
Chemical Formula C10H8O6
Full Name 1,2,4,5-Cyclohexanetetracarboxylic dianhydride
Molecular Weight 224.17 g/mol
Synonyms Hexahydro-1H,3H-furo[3,4-f][2]benzofuran-1,3,5,7-tetrone, Tetrahydrobenzo[1,2-c:4,5-c']difuran-1,3,5,7(3aH,7aH)-tetraone
Classification / Family Dianhydride building block, Ionic conducting membranes, Polyimides, Polyesters

Chemical Structure

1,2,4,5-cyclohexanetetracarboxylic dianhydride (HPMDA) chemical structure, CAS 2754-41-8.
1,2,4,5-cyclohexanetetracarboxylic dianhydride (HPMDA) chemical structure, CAS 2754-41-8

Product Details

Purity >99%
Melting Point Tm = 240 °C
Appearance White to off-white powder/crystal

MSDS Documentation

1,2,4,5-cyclohexanetetracarboxylic dianhydride (HPMDA)1,2,4,5-cyclohexanetetracarboxylic dianhydride (HPMDA) MSDS Sheet

Literature and Reviews

  1. Functional polyimides based on diamine containing diarylethylene moieties and their photochromic mechanism studies, W. Huang et al., Polym. Chem., 11, 6701(2020); DOI: 10.1039/d0py01084g.
  2. Lyotropic liquid crystalline property and organized structure in high proton-conductive sulfonated semialicyclic oligoimide thin film, Y. Yao et al., ACS Omega, 8, 7470-7478(2023); DOI: 10.1021/acsomega.2c06398.
  3. Optically transparent sulfur-containing polyimide-TiO2 nanocomposite films with high refractive index and negative pattern formation from poly(amic acid)-TiO2 nanocomposite film, J.-G. Liu et al., Chem. Mater., 20, 273-281(2008); DOI: 10.1021/cm071430s.
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