1-Acetylpyrene
CAS Number 870718-97-1
Latest Products, Non-Heterocyclic Building Blocks, Monomers, Materials
Crystalline Pyrene Derivative
Widely used as photoinitiator and environment-sensitive fluorophore, >98% purity
Specifications | MSDS | Literature and Reviews
1-Acetylpyrene is a derivative of polycyclic hydrocarbons pyrene featuring an acetyl group on the first carbon of the flat fused pyrene ring. With crystal structures based on π⋯π-dimers, polymorphs β and γ 1-acetylpyrene show intense luminesce from blue to green, while its α polymorph, with a herringbone packing motif, is non-luminescent. Conjugated pyrene is a a sensitive fluorescence probe where its emission is highly sensitive to medium polarity and the molecular stacking.
1-Acetylpyrene emits broad dimer-based fluorescence centred around 390-410 nm due to strong π-π stacking interactions in solution. Sensors based on 1-pyrenecarboxaldehyde exhibit ultra-low detection limits of 0.33 μM for hydrazine by triggering rapid optical changes visible to the naked eye. 1-Acetylpyrene induces type I binding spectra with human cytochrome P450 2A13 and efficiently oxidized by the enzyme to several oxygenated products.
General Information
| CAS Number | 3264-21-9 |
|---|---|
| Chemical Formula | C18H12O |
| Full Name | 1-Acetylpyrene |
| Molecular Weight | 244.29 g/mol |
| Synonyms | 1-(Pyren-1-yl)ethan-1-one, 1-(1-Pyrenyl)ethanone |
| Classification / Family | Pyrene, semiconductor synthesis intermediates, OLED, OFETs, organic photovoltaics |
Chemical Structure
Product Details
| Purity | >98% (HNMR) |
|---|---|
| Melting Point |
86-89 °C (lit.)
|
| Appearance | White to yellowish powder/crystals |
MSDS Documentation
1-Acetylpyrene MSDS SheetLiterature and Reviews
- D. Tchoń et al. (2019), Three new polymorphs of 1,8-diacetylpyrene: a material with packing-dependent luminescence properties and a testbed for crystal structure prediction, J. Mater. Chem. C, 9, 2491-2503; DOI: 10.1039/D0TC05522K.
- T. Shimada et al. (2016), Oxidation of pyrene, 1-hydroxypyrene, 1-nitropyrene and 1-acetylpyrene by human cytochrome P450 2A13, Xenobiotica, 46(3), 211–224; DOI: 10.3109/00498254.2015.1069419.
- D. Kasundra et al. (2026), Pyrene aided dual mode fluorophore sensor for trace hydrazine detection in real environmental samples: Design, mechanism and DFT insights, Spectrochim. Acta A Mol. Biomol. Spectrosc., 348, 127238; DOI: 10.1016/j.saa.2025.127238.