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CAS Number 1762-34-1

Chemistry Building Blocks, Heterocyclic Building Blocks, Materials, Monomers

Product Code B1471-10g
Price £110 ex. VAT

A frequent bipyridyl ligand and intermediate

Available for the synthesis of organometallic complexes, photosensitizers, and pharmaceuticals applications

Specifications | MSDS | Literature and Reviews

5,5'-Dimethyl-2,2'-bipyridine (or 5,5'-Dimethyl-2,2'-bipyridyl), CAS number 1762-34-1, is a bipyridyl derivative with dimethyl functional groups at 5,5-positions. Dimethyl groups can be further oxidised to prepare 2,2'-bipyridine-5,5'-dicarboxylic acid. 5,5'-Dimethyl-2,2'-bipyridine is widely used as a ligand for organometallic chemical synthesis and pharmaceuticals applications.

Exhibiting high luminescence for G-quadruplex DNA, iridium(III) complex [Ir(pbi)2(5,5'-dmbpy)]PF6 is employed to construct G-quadruplex-based assay for protein tyrosine kinase-7 (PTK7) in aqueous solution. PTK7 is an important biomarker for a range of leukaemia and solid tumours. 5,5′-dimethyl -2, 2′-dipyridyl demonstrates significant activity against embryos and was capable of arresting development at a number of stages of embryogenesis.

General Information

CAS Number 1762-34-1
Chemical Formula C12H12N2
Full Name 5,5′-Dimethyl-2,2′-bipyridine
Molecular Weight 184.24 g/mol
Synonyms 5,5'-Dimethyl-2,2'-bipyridyl, 5,5'-dmbpy
Classification / Family Bipyridine derivatives, Semiconductor synthesis intermediates, OLED, OFETs, organic photovoltaics

Chemical Structure

5,5'-Dimethyl-2,2'-bipyridine chemical structure, 1762-34-1
5,5'-Dimethyl-2,2'-bipyridine (5,5'-dmbpy) chemical structure, CAS 1762-34-1

Product Details

Purity >98% (1H NMR)
Melting Point Tm = 115 °C
Appearance Off white powder

MSDS Documentation

5,5'-Dimethyl-2,2'-bipyridine5,5'-Dimethyl-2,2'-bipyridine MSDS Sheet

Literature and Reviews

  1. Luminescence switch-on detection of protein tyrosine kinase-7 using a G-quadruplex-selective probe, Chem. Sci., 6, 4284-4290 (2015); DOI: 10.1039/C5SC01320H.
  2. A novel Au(III) complex with the 5,5′-dimethyl-2,2′-bipyridine ligand: Synthesis, characterization, X-ray crystal structure and biological evaluation, T. Kondori et al., Polyhedron, 210, 115513 (2021); 10.1016/j.poly.2021.115513.
  3. Supramolecular architectures of mononuclear nickel(II) and homobinuclear copper(II) complexes square with the 5,5’dimethyl-2,2’-bipyridine ligand: Syntheses, Crystal structures and Hirshfeld surface analyses, W. Maalej et al., J. Mol. Struct., 1250, 131727 (2022); DOI: 10.1016/j.molstruc.2021.131728.

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