Amorphous Biodegradable and Biocompatible Polymer
With excellent flexibility and controlled biodegradability
Specifications | Pricing and Options | MSDS | Literature and Reviews
Poly(D,L-lactide), also known as PDLLA, is an amorphous biodegradable and biocompatible polymer derived from a racemic mixture of D-lactide and L-lactide. Due to its biocompatibility, excellent flexibility, and controlled biodegradability, applications are primarily in the biomedical and cosmetic fields.
PDLLA is used in the fabrication of bioabsorbable dissolvable sutures to enhance wound contraction, increase collagen, and promote tissue regeneration. With PDLLA, sutures can be engineered to have the necessary strength and flexibility for various surgical applications.
Fracture fixation devices, such as screws, plates, and anchors to provide biomechanical support as bone heals, are also a popular application of PDLLA. These implants are completely broken down by the body into harmless substances which are well-tolerated, causing no irritation to surrounding soft tissues and reducing the risk of adhesions.
Capable of stimulating collagen synthesis, PDLLA has been explored for its potential to improve skin elasticity, reduce fine wrinkles, and remodel scars. Collagen-stimulating PDLLA microparticles are used in cosmetic surgery to restore lost volume, improve skin texture, and reduce wrinkles by triggering the body's natural collagen production over time.
General Information
| CAS Number | 51056-13-9, 26680-10-4 |
|---|---|
| Chemical Formula | (C6H8O4)n |
| Synonyms | PDLLA, Poly(D,L-lactic acid) |
| Molecular Weight | Mn = 38,153, Mw = 84,523, PDI = 2.21 |
| Intrinsic viscosity [η] | 0.64 dL/g (25 ℃ in Chloroform) |
| Specific Rotation | -1.32 ° |
| Solubility | Chloroform, dichloromethane, DMF |
| Form | White powder |
| Storage | 2 – 8 °C |
| Classification or Family | Polylactide, Biodegradable polymers, Biocompatible polymers, Drug delivery |
Chemical Structure
Pricing
| Batch | Quantity | Price |
|---|---|---|
| M2573A1 | 1 g | £75 |
| M2573A1 | 5 g | £210 |
| M2573A1 | 10 g | £330 |
MSDS Documentation
Poly(D,L-lactide) MSDS sheetLiterature and Reviews
- K. Lee et al. (2024); Poly-d,l-lactic Acid (PDLLA) Application in Dermatology: A Literature Review, Polymers, 16(18), 2583; DOI: 10.3390/polym16182583.
- J. Wan et al, (2025); Evaluating Poly-D,L-Lactic Acid for Lower Eyelid Rejuvenation: Efficacy and Safety, J. Cosmet. Dermatol., 24 (3), e70058; DOI: 10.1111/jocd.70058.
- X. Wan et al. (2025); Multimaterial Shape Memory Polymer Fibers for Advanced Drug Release Applications, Adv. Fiber Mater., 7, 1576–1589; DOI: 10.1007/s42765-025-00571-4.