FREE shipping to on qualifying orders when you spend or more, processed by Ossila BV. All prices ex. VAT. Qualifying orders ship free worldwide! Fast, secure, and backed by the Ossila guarantee. It looks like you are visiting from , click to shop in or change country. Orders to the EU are processed by our EU subsidiary.

It looks like you are using an unsupported browser. You can still place orders by emailing us on info@ossila.com, but you may experience issues browsing our website. Please consider upgrading to a modern browser for better security and an improved browsing experience.

1,1':4',1'':4'',1'''-Quarterphenyl-3,3''',5,5'''-tetracarboxylic acid

CAS Number 921619-91-2

Chemistry Building Blocks, Materials, MOF Ligands, Porous Organic Frameworks


Product Code B3101-500mg
Price $138 ex. VAT

Quality assured

Expert support

Volume discounts

Worldwide shipping

Fast and secure


Metal Organic Frameworks (MOFs) Quarterphenyl Ligand

A rigid linear ligand linker for MOFs in applications of drug delivery and temperature-dependent luminescence


1,1':4',1'':4'',1'''-quaterphenyl-3,3''',5,5'''-tetracarboxylic acid (H4QPTC) is a linear quarterphenyl with two carboxylic acid groups at 3,5-positions of each end benzene rings.

MOF with the chemical formula (NH2(CH3)2[Zn3(L)2·3.5DMF]) (MOF-Zn-H4QPTC) (H4L = 1,1′,4′,1″,4″,1‴-quaterphenyl-3,5,3‴,5‴-tetracarboxylic acid) shows an unusual 4,8-connected 3D structure. The drug 5-fluorouracil (5-FU) uptake into the complex was about 22.5 wt.% per gram of dehydrated form of MOF-Zn-H4QPTC. 5-Fu is then released in a highly controlled and progressive fashion with 92% of the drug being released in 120 h.

Anionic MOF with In(III) centres and tetracarboxylic acid ligands (MOF-In-H4QPTC) shows kinetic trapping behaviour of hydrogen. With piperazinium dications in its pores, the framework exhibits hysteretic hydrogen adsorption. 

Ratiometric thermometer encapsulating luminescent perylene dye into the pores of a europium metal–organic framework (MOF-Eu-H4QPTC), exhibits highly temperature dependent luminescence intensity ratio over the physiological temperature range, with a maximum sensiti­vity of 1.28% °C−1 at 20 °C.

General Information

CAS Number 921619-91-2
Chemical Formula C28H18O8
Full Name 1,1':4',1'':4'',1'''-quaterphenyl-3,3''',5,5'''-tetracarboxylic acid
Molecular Weight 482.44 g/mol
Synonyms H4QPTC, Quarterphenyl-3,3''',5,5'''-tetracarboxylic acid
Classification / Family Quarterphenyl, MOF ligands, 

Chemical Structure

921619-91-2 - quarterphenyl-3,3''',5,5'''-tetracarboxylic acid chemical structure
1,1':4',1'':4'',1'''-quaterphenyl-3,3''',5,5'''-tetracarboxylic acid (H4QPTC) Chemical Structure, 921619-91-2

Product Details

Purity >98%
Melting Point n.a.
Appearance Off White powder/crystal

MSDS Documentation

921619-91-2 - 1,1':4',1'':4'',1'''-quaterphenyl-3,3''',5,5'''-tetracarboxylic acid1,1':4',1'':4'',1'''-Quaterphenyl-3,3''',5,5'''-tetracarboxylic acid MSDS Sheet

Literature and Reviews

  1. A new (4,8)-connected topological MOF as potential drug delivery, Q. Li et al., Inorg. Chem. Commun., 55, 8-10 (2015); DOI: 10.1016/j.inoche.2015.02.023.
  2. Loading Photochromic Molecules into a Luminescent Metal–Organic Framework for Information Anticounterfeiting, Z. Li et al., Angew. Chem., 131 (50), 18193-18199 (2019); DOI: 10.1002/ange.201910467.
  3. Cation-induced kinetic trapping and enhanced hydrogen adsorption in a modulated anionic metal–organic framework, S. Yang et al., Nat. Chem., 1, 487–493 (2009); DOi: 10.1038/nchem.333
  4. Our journey of developing dual-emitting metal-organic framework-based fluorescent sensors, T. Xia et al., ZAAC, 648 (9), e202100355 (2022); DOI: 10.1002/zaac.202100355.
  5. Energy Transfer in Metal–Organic Frameworks for Fluorescence Sensing, J. Wang et al., ACS Appl. Mater. Interfaces, 14 (8), 9970–9986 (2022); DOI: 10.1021/acsami.1c24759.
  6. Dual-Emitting MOF⊃Dye Composite for Ratiometric Temperature Sensing, Y. Cui et al., 27 (8), 1420-1425 (2015); DOI: 10.1002/adma.201404700.

To the best of our knowledge the information provided here is accurate. The values provided are typical at the time of manufacture and may vary over time and from batch to batch. Products may have minor cosmetic differences (e.g. to the branding) compared to the photos on our website. All products are for laboratory and research and development use only.

Return to the top