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Phenyl 1-hydroxy-2-naphthoate

CAS Number 132-54-7

Liquid Crystals, Materials, Optoelectronic Materials

Product Code M2367A1-25g
Price £125 ex. VAT

Phenyl 1-hydroxy-2-naphthoate, liquid crystal Intermediate

Intermediate for the synthesis of natural products and anti-carcinogenic compounds, liquid crystal intermediates.

Specifications | Pricing and Options | MSDS | Literature and Reviews

Phenyl 1-Hydroxy-2-naphthoate (PHN), CAS number 132-54-7, is a phenyl ester of 1-hydroxy-2-naphthoic acid. Hydroxynaphthoate derivatives are well known for their biological and medicinal properties. The 1-hydroxy-2-naphthoate moiety has been discovered in natural products such as the cytotoxic compounds 3-hydroxymollugin and 3-methoxymollugin. For their biological and medicinal properties, hydroxynaphthoates play an important role in drug discovery and they have been used as intermediates for the synthesis of the anti-carcinogenic compounds.

Research also shows that both methyl 1-hydroxy-2-naphthoate and ethyl 1,6-dihydroxy-2-naphthoate develop anti-inflammatory activity, while 1-hydroxy-2-naphthoic acid itself has been recognized as an antibacterial agent.

Monomer for drug discovery

Monomer for drug discovery

1-hydroxy-2-naphthoate moiety has been discovered in natural products

Exhibiting solvatochromism

Exhibiting solvatochromism

Attributed to the intramolecular proton transfer

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High purity

High purity

>98% High purity

Chemical Structure

Phenyl 1-Hydroxy-2-naphthoate (PHN), CAS# 132-54-7
Chemical structure of Phenyl 1-hydroxy-2-naphthoate (PHN), CAS 132-54-7

General Information

CAS Number 132-54-7
Chemical Formula C17H12O3
Molecular Weight 264.28
Full Name Phenyl 1-hydroxy-2-naphthoate
Synonyms 1-Hydroxy-2-naphthoic acid phenyl ester, 2-Phenoxycarbonyl-1-naphthol, Phenyl 1-hydroxy-2-naphthalate
Classification / Family Hydroxynaphthoate derivatives, Anti-inflammatory activity, Antibacterial

Product Details

Purity >98% (1HNMR)
Form Off-white powder/crystals
Melting Point 93.0 to 96.0 °C


Batch Quantity Price
M2367A1 25 g £125
M2367A1 50 g £220
M2367A1 100 g £340

MSDS Documentation

Phenyl 1-hydroxy-2-naphthoate MSDSPhenyl 1-hydroxy-2-naphthoate MSDS Sheet

Literature and Reviews

  1. Solvatochromism and intramolecular hydrogen-bonding assisted dipole moment of phenyl 1-hydroxy-2-naphthoate in the ground and excited states, I. Sıdır et al., J. Mol. Liq., 221, 972-985 (2016); DOI: 10.1016/j.molliq.2016.06.019.
  2. Infrared Spectrum and UV-Induced Photochemistry of Matrix-Isolated Phenyl 1-Hydroxy-2-Naphthoate, I. Sıdır et al., Photochem., 1(1), 10-25 (2021); DOI: 10.3390/photochem1010002.
  3. Crystal structure of phenyl 1-hydroxy-2-naphthoate, an unexpected product from an attempted aryl aryl coupling reaction, K Peters et al., Z. Kristallogr. Cryst. Mater., 210 (3), 210-211 (1995); DOI: 10.1524/zkri.1995.210.3.210.
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